|
Strains
included in the databases.
Patterns
will be recorded from all strains that are not M. tuberculosis
(the human adapted form of M. bovis). Because of the
strict clonality of this group of organisms we can define M. bovis
group strains as
those strains in the M.tuberculosis complex that lack the
chromosomal region RD9 (1).
The
databases will therefore include patterns derived from M. africanum
(West African), M. microti, llama associated strains,
goat associated strains (Mycobacterium bovis subsp. caprae
comb. nov) as well as spoligotypes derived from traditional bovine
isolates. These strains will also lack spoligotype spacer 39 and
spacer 9. However, this is not diagnostic - strains of M. tuberculosis
may also lack these spacers.
(1) A new evolutionary scenario for the Mycobacterium tuberculosis
complex. Brosch et al PNAS 2002
.
|